Investigation of Blood Count-Based Inflammatory Biomarkers as Predictors of Response to Dupilumab Treatment in Patients with Chronic Rhinosinusitis with Nasal Polyps

• Main Authors: Michael Habenbacher (Author), Ulrich Moser (Author), Ahmed Abaira (Author), Peter Kiss (Author), Clemens Holzmeister (Author), Jakob Pock (Author), Katharina Walla (Author), Angelika Lang (Author), Alexandros Andrianakis (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2024-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background/Objectives: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often resistant to standard treatments. Dupilumab, a monoclonal antibody targeting the IL-4α receptor, has shown efficacy in CRSwNP, but a significant subset of patients do not respond to this t...