Excipient Interactions in Glucagon Dry Powder Inhaler Formulation for Pulmonary Delivery

• Principais autores: Md Abdur Rashid (Autor), Amged Awad Elgied (Autor), Yahya Alhamhoom (Autor), Enoch Chan (Autor), Llew Rintoul (Autor), Ayman Allahham (Autor), Nazrul Islam (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2019-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purpose: This study describes the development and characterization of glucagon dry powder inhaler (DPI) formulation for pulmonary delivery. Lactose monohydrate, as a carrier, and L-leucine and magnesium stearate (MgSt) were used as dispersibility enhancers for this formulation. Methods: Using Fourie...