Cocrystallization of Gefitinib Potentiate Single-Dose Oral Administration for Lung Tumor Eradication via Unbalancing the DNA Damage/Repair
Gefitinib (GEF) is a clinical medication for the treatment of lung cancer targeting the epidermal growth factor receptor (EGFR). However, its efficacy is remarkably limited by low solubility and dissolution rates. In this study, two cocrystals of GEF with co-formers were successfully synthesized usi...
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Main Authors: | Muhammad Inam (Author), Yi Yang (Author), Jialin Hu (Author), Jiena Zheng (Author), Wenxia Deng (Author), You Zhou (Author), Jialong Qi (Author), Chuanshan Xu (Author), Guihong Chai (Author), Yuanye Dang (Author), Wenjie Chen (Author) |
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Format: | Book |
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MDPI AG,
2023-11-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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