Molecular analysis of translocations associated with Ewing sarcoma: case report
ABSTRACT We report the case of a 25-year-old female patient having a large lesion in the right breast. The core biopsy revealed a high-grade fusocellular neoplasm. Immunostains show no evidence of a specific line of differentiation. The patient underwent radical surgery and adjuvant treatment. Due t...
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Sociedade Brasileira de Patologia Clínica.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_16b1e34f4a3a431da82c10c1a04889c5 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Leonardo R. Soares |e author |
| 700 | 1 | 0 | |a Hugo A. Bayeh |e author |
| 700 | 1 | 0 | |a Izabela Cristina Albuquerque |e author |
| 700 | 1 | 0 | |a Marise A. R. Moreira |e author |
| 700 | 1 | 0 | |a Miguel A. C. Coutinho |e author |
| 700 | 1 | 0 | |a Debora F. Rodrigues |e author |
| 700 | 1 | 0 | |a Paula O. C. Queiroz |e author |
| 700 | 1 | 0 | |a Ruffo Freitas-Junior |e author |
| 245 | 0 | 0 | |a Molecular analysis of translocations associated with Ewing sarcoma: case report |
| 260 | |b Sociedade Brasileira de Patologia Clínica. | ||
| 500 | |a 1678-4774 | ||
| 500 | |a 10.5935/1676-2444.20190020 | ||
| 520 | |a ABSTRACT We report the case of a 25-year-old female patient having a large lesion in the right breast. The core biopsy revealed a high-grade fusocellular neoplasm. Immunostains show no evidence of a specific line of differentiation. The patient underwent radical surgery and adjuvant treatment. Due to the immunohistochemical profile and the rosette arrangement in fusocellular injury, a molecular evaluation of translocations associated to the Ewing sarcoma (ES) was made. However, translocations commonly associated with this disease [t(11;22)(q24;q12)] were not observed. The present report can contribute to the diagnostic investigation of similar cases and to the pre-test orientation of the molecular evaluation. | ||
| 546 | |a EN | ||
| 690 | |a breast neoplasms | ||
| 690 | |a pathology | ||
| 690 | |a Ewing sarcoma | ||
| 690 | |a Pathology | ||
| 690 | |a RB1-214 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Jornal Brasileiro de Patologia e Medicina Laboratorial | |
| 787 | 0 | |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000200218&tlng=en | |
| 787 | 0 | |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000200218&tlng=pt | |
| 787 | 0 | |n http://www.scielo.br/pdf/jbpml/v55n2/1676-2444-jbpml-55-02-0218.pdf | |
| 787 | 0 | |n http://www.scielo.br/pdf/jbpml/v55n2/pt_1676-2444-jbpml-55-02-0218.pdf | |
| 787 | 0 | |n https://doaj.org/toc/1678-4774 | |
| 856 | 4 | 1 | |u https://doaj.org/article/16b1e34f4a3a431da82c10c1a04889c5 |z Connect to this object online. |