Smoking cessation in the elderly as a sign of susceptibility to symptomatic COVID-19 reinfection in the United States

BackgroundWe aimed to clarify the relationship between coronavirus disease 2019 (COVID-19) reinfection and basic disease and smoking status.MethodsThe electronic health records of 165,320 patients with COVID-19 from January 1, 2020, to August 27, 2021, were analyzed. Data on age, race, sex, smoking...

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Main Authors: Wataru Ando (Author), Takeshi Horii (Author), Mitsuki Jimbo (Author), Takayuki Uematsu (Author), Koichiro Atsuda (Author), Hideaki Hanaki (Author), Katsuya Otori (Author)
Format: Book
Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Wataru Ando  |e author 
700 1 0 |a Wataru Ando  |e author 
700 1 0 |a Takeshi Horii  |e author 
700 1 0 |a Mitsuki Jimbo  |e author 
700 1 0 |a Takayuki Uematsu  |e author 
700 1 0 |a Koichiro Atsuda  |e author 
700 1 0 |a Hideaki Hanaki  |e author 
700 1 0 |a Katsuya Otori  |e author 
700 1 0 |a Katsuya Otori  |e author 
245 0 0 |a Smoking cessation in the elderly as a sign of susceptibility to symptomatic COVID-19 reinfection in the United States 
260 |b Frontiers Media S.A.,   |c 2022-11-01T00:00:00Z. 
500 |a 2296-2565 
500 |a 10.3389/fpubh.2022.985494 
520 |a BackgroundWe aimed to clarify the relationship between coronavirus disease 2019 (COVID-19) reinfection and basic disease and smoking status.MethodsThe electronic health records of 165,320 patients with COVID-19 from January 1, 2020, to August 27, 2021, were analyzed. Data on age, race, sex, smoking status (never, current, former), and basic disease were analyzed using Cox proportional hazard models.ResultsIn total, 6,133 patients (3.7%) were reinfected. The overall reinfection rate for never, current, and former smokers was 4.2, 3.5, and 5.7%, respectively. Although the risk of reinfection was highest among former smokers aged ≥65 years (7.7% [422/5,460]), the reinfection rate among current smokers aged ≥65 years was 6.2% (341/5,543). Among reinfected patients, the number of basic diseases was higher in former smokers (2.41 ± 1.16) than in current (2.28 ± 1.07, P = 0.07) and never smokers (2.07 ± 1.05, P < 0.001). Former smokers who are older may have been exposed to factors that increase their risk of symptomatic COVID-19 reinfection. 
546 |a EN 
690 |a COVID-19 
690 |a smoking 
690 |a reinfection 
690 |a data analysis 
690 |a database 
690 |a United States 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Frontiers in Public Health, Vol 10 (2022) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fpubh.2022.985494/full 
787 0 |n https://doaj.org/toc/2296-2565 
856 4 1 |u https://doaj.org/article/16b5cc901b554ae3b41115d6c463cf7d  |z Connect to this object online.