Cover Image

AFK-PD alleviated osteoarthritis progression by chondroprotective and anti-inflammatory activity

Osteoarthritis (OA) is the most prevalent cartilage degenerative and low-grade inflammatory disease of the whole joint. However, there are currently no FDA-approved drugs or global regulatory agency-approved treatments OA disease modification. Therefore, it's essential to explore novel effectiv...

Full description

Saved in:

Bibliographic Details
Main Authors:	Zhuang Qian (Author), Jie Xu (Author), Lei Zhang (Author), Qian Deng (Author), Zhenlin Fan (Author), Xueqiang Guo (Author), Zhuo Liang (Author), Weiyun Wang (Author), Lei Wang (Author), Xiaohua Liao (Author), Wenjie Ren (Author)
Format:	Book
Published:	Frontiers Media S.A., 2024-08-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Application of chondroprotective agents to inhibit osteodestructive processes in the subchondral bone in patients with osteoarthritis
by: О. А. Gromova, et al.
Published: (2022)

Bioactive components and potential mechanisms of Biqi Capsule in the treatment of osteoarthritis: based on chondroprotective and anti-inflammatory activity
by: Ziyue Jia, et al.
Published: (2024)

A putative Chondroprotective role for IL-1β and MPO in herbal treatment of experimental osteoarthritis
by: Nora M. Aborehab, et al.
Published: (2017)

Chondroprotective Effects of 4,5-Dicaffeoylquinic Acid in Osteoarthritis through NF-κB Signaling Inhibition
by: Goeun Jang, et al.
Published: (2022)

Evaluation of the effect of an ayurvedic formulation Myostaal Forte tablets on chondroprotective biomarkers in an experimental model of osteoarthritis in rats
by: Shetty YC, et al.
Published: (2021)

Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study
by: Qing Ding, et al.
Published: (2023)

Selonsertib Alleviates the Progression of Rat Osteoarthritis: An in vitro and in vivo Study
by: Jiyuan Yan, et al.
Published: (2021)

Tabetri™ (Tabebuia avellanedae Ethanol Extract) Ameliorates Osteoarthritis Symptoms Induced by Monoiodoacetate through Its Anti-Inflammatory and Chondroprotective Activities
by: Jae Gwang Park, et al.
Published: (2017)

Overexpression of SOX9 alleviates the progression of human osteoarthritis in vitro and in vivo
by: Ouyang Y, et al.
Published: (2019)

Chondroprotective Mechanism of Eucommia ulmoides Oliv.-Glycyrrhiza uralensis Fisch. Couplet Medicines in Knee Osteoarthritis via Experimental Study and Network Pharmacology Analysis
by: Wang P, et al.
Published: (2023)

Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice
by: Zhen Li, et al.
Published: (2023)

A Novel Rose Hip Preparation with Enhanced Anti-Inflammatory and Chondroprotective Effects
by: Joseph Schwager, et al.
Published: (2014)

Jianpi Yangzheng Xiaozheng decoction alleviates gastric cancer progression via suppressing exosomal PD-L1
by: Yanzhen Chen, et al.
Published: (2023)

Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis
by: Huangming Zhuang, et al.
Published: (2023)

The Synergistic Effects of <i>Corbicula fluminea</i> and <i>Sarcodia montagneana</i> on Alleviating Systemic Inflammation and Osteoarthritis Progression
by: Tse-Hung Huang, et al.
Published: (2023)

Trachelogenin alleviates osteoarthritis by inhibiting osteoclastogenesis and enhancing chondrocyte survival
by: Tao Jiang, et al.
Published: (2024)

Mesenchymal Stem Cell-Derived Exosomes Modulate Chondrocyte Glutamine Metabolism to Alleviate Osteoarthritis Progression
by: Kai Jiang, et al.
Published: (2021)

Quercetin Alleviates Osteoarthritis Progression in Rats by Suppressing Inflammation and Apoptosis via Inhibition of IRAK1/NLRP3 Signaling
by: Li W, et al.
Published: (2021)

Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model
by: Jingtao Wu, et al.
Published: (2023)

Taraxerone inhibits M1 polarization and alleviates sepsis-induced acute lung injury by activating SIRT1
by: Lang Deng, et al.
Published: (2024)

ICOS/ICOSLG and PD-1 Co-Expression is Associated with the Progression of Colorectal Precancerous- Carcinoma Immune Microenvironment
by: Zhang Y, et al.
Published: (2023)

Angelicin Alleviates Post-Trauma Osteoarthritis Progression by Regulating Macrophage Polarization via STAT3 Signaling Pathway
by: Zhansong Tian, et al.
Published: (2021)

Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology
by: Nanxing Yi, et al.
Published: (2022)

Anti-Inflammatory and Antioxidant Effects of Irigenen Alleviate Osteoarthritis Progression through Nrf2/HO-1 Pathway
by: Xuan Fang, et al.
Published: (2024)

Taurine alleviates endoplasmic reticulum stress in the chondrocytes from patients with osteoarthritis
by: Yiqun Bian, et al.
Published: (2018)

Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect
by: Rui Lu, et al.
Published: (2021)

Inhibition of Synovial Macrophage Pyroptosis Alleviates Synovitis and Fibrosis in Knee Osteoarthritis
by: Li Zhang, et al.
Published: (2019)

Prevalence of osteoarthritis and association between smoking patterns and osteoarthritis in China: a cross-sectional study
by: He Qian-Qian, et al.
Published: (2018)

Percentages of PD-1+CD4+T cells and PD-L1+DCs are increased and sPD-1 level is elevated in patients with immune thrombocytopenia
by: Yingying Wang, et al.
Published: (2018)

Anti-Inflammatory and Chondroprotective Effects Induced by Phenolic Compounds from Onion Waste Extracts in ATDC-5 Chondrogenic Cell Line
by: Mónica Paesa, et al.
Published: (2022)

Formulation design and characterization of a non-ionic surfactant based vesicular system for the sustained delivery of a new chondroprotective agent
by: Muhammad Imran Khan, et al.
Published: (2015)

Extracellular vesicles from synovial fluid-derived mesenchymal stem cells confer chondroprotective effects on in vitro and in vivo osteoarthritic chondrocytes
by: Haixiang Liang, et al.
Published: (2023)

Prognostic and Clinicopathological Significance of PD-L1 in Patients With Bladder Cancer: A Meta-Analysis
by: Lei Zhu, et al.
Published: (2019)

Pyroptosis in the Initiation and Progression of Atherosclerosis
by: Zhengtao Qian, et al.
Published: (2021)

Activation of Adenosine A3 Receptor Alleviates TNF-α-Induced Inflammation through Inhibition of the NF-κB Signaling Pathway in Human Colonic Epithelial Cells
by: Tianhua Ren, et al.
Published: (2014)

ESC-sEVs alleviate non-early-stage osteoarthritis progression by rejuvenating senescent chondrocytes via FOXO1A-autophagy axis but not inducing apoptosis
by: Kai Feng, et al.
Published: (2024)

Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
by: Zhou Guo, et al.
Published: (2022)

Anti-PD-1/PD-L1 for nasopharyngeal carcinoma: a comprehensive analysis of registered trials on ClinicalTrials.gov
by: Zelei Dai, et al.
Published: (2023)

Madecassic Acid Ameliorates the Progression of Osteoarthritis: An in vitro and in vivo Study
by: Fu X, et al.
Published: (2022)

Gene therapies for osteoarthritis: progress and prospects
by: Anais Defois, et al.
Published: (2024)