Poly-herbal tablet formulation by design expert tool and in vitro anti-lipase activity

Abstract Background Traditional medicine being ethnic is preferred worldwide even in these modern days. Obesity is a lifestyle disorder. Many chemically synthesized medicines are available. Poly-herbal medicines can be one of the safest alternatives with less side effects in treating obese patients....

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Main Authors: Amruta Balekundri (Author), Amit Shahapuri (Author), Mrityunjaya Patil (Author)
Format: Book
Published: SpringerOpen, 2020-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Amruta Balekundri  |e author 
700 1 0 |a Amit Shahapuri  |e author 
700 1 0 |a Mrityunjaya Patil  |e author 
245 0 0 |a Poly-herbal tablet formulation by design expert tool and in vitro anti-lipase activity 
260 |b SpringerOpen,   |c 2020-12-01T00:00:00Z. 
500 |a 10.1186/s43094-020-00131-0 
500 |a 2314-7253 
520 |a Abstract Background Traditional medicine being ethnic is preferred worldwide even in these modern days. Obesity is a lifestyle disorder. Many chemically synthesized medicines are available. Poly-herbal medicines can be one of the safest alternatives with less side effects in treating obese patients. Results The in vitro anti-lipase activity was carried out for a different concentration. The formulation of the poly-herbal tablets was designed using the Design Expert software. The pre-compression and post-compression studies show that the formulation F6 showed better results of all the formulations designed. Stability study results showed that the poly-herbal tablets were stable throughout the studies. Conclusion The results show that F6 is the better formulation based on the tablet evaluation, and all the extracts showed inhibitory activity against pancreatic lipase indicating its active role in the treatment of obesity. 
546 |a EN 
690 |a Poly-herbal tablet 
690 |a In vitro anti-lipase activity 
690 |a Design expert tool 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Future Journal of Pharmaceutical Sciences, Vol 6, Iss 1, Pp 1-11 (2020) 
787 0 |n https://doi.org/10.1186/s43094-020-00131-0 
787 0 |n https://doaj.org/toc/2314-7253 
856 4 1 |u https://doaj.org/article/16cdca82fd3749da9aa3e8ded4a6f6e4  |z Connect to this object online.