Global impact of varicella vaccination programs

Although varicella is usually a mild and self-limited disease, complications can occur. In 1998, the World Health Organization recommended varicella vaccination for countries where the disease has a significant public health burden. Nonetheless, concerns about a shift in the disease to older groups,...

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Bibliographic Details
Main Authors: Fernanda Hammes Varela (Author), Leonardo Araújo Pinto (Author), Marcelo Comerlato Scotta (Author)
Format: Book
Published: Taylor & Francis Group, 2019-03-01T00:00:00Z.
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Summary:Although varicella is usually a mild and self-limited disease, complications can occur. In 1998, the World Health Organization recommended varicella vaccination for countries where the disease has a significant public health burden. Nonetheless, concerns about a shift in the disease to older groups, an increase in herpes zoster in the elderly and cost-effectiveness led many countries to postpone universal varicella vaccine introduction. In this review, we summarize the accumulating evidence, available mostly from high and middle-income countries supporting a high impact of universal vaccination in reductions of the incidence of the disease and hospitalizations and its cost-effectiveness. We have also observed the effect of herd immunity and noted that there is no definitive and consistent association between vaccination and the increase in herpes zoster incidence in the elderly.
Item Description:2164-5515
2164-554X
10.1080/21645515.2018.1546525