Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

• Main Authors: Bin Jiang (Author), Dongdong Wang (Author), Yunfu Hu (Author), Wenxuan Li (Author), Fengjiang Liu (Author), Xudong Zhu (Author), Xiaoyu Li (Author), Hanwen Zhang (Author), Hui Bai (Author), Qing Yang (Author), Xiuna Yang (Author), Jingjing Ben (Author), Qi Chen (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Chronic inflammatory response plays a prominent role in obesity-related nonalcoholic fatty liver disease (NAFLD). However, the intrahepatic triggering mechanism of inflammation remains obscure. This study aimed to elucidate the role of serum amyloid A1 (SAA1), an acute-phase response prot...