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Long-Term Treatment With Ranirestat (AS-3201), a Potent Aldose Reductase Inhibitor, Suppresses Diabetic Neuropathy and Cataract Formation in Rats

We investigated the chronic functional and histopathological changes in the sciatic nerve and lens of streptozotocin (STZ)-diabetic rats and evaluated the preventive effects of ranirestat (AS-3201), a potent aldose reductase inhibitor, on these changes. Sorbitol levels in the sciatic nerve and lens,...

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Main Authors:	Takafumi Matsumoto (Author), Yoshiyuki Ono (Author), Akemi Kuromiya (Author), Kaoru Toyosawa (Author), Yoshinaka Ueda (Author), Vera Bril (Author)
Format:	Book
Published:	Elsevier, 2008-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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