Potential mechanism prediction of indole-3-propionic acid against diminished ovarian reserve via network pharmacology, molecular docking and experimental verification

• Автори: Ahui Liu (Автор), Zhijun Liu (Автор), Haofei Shen (Автор), Wenjing Du (Автор), Yanbiao Jiang (Автор), Liyan Wang (Автор), Rui Zhang (Автор), Panpan Jin (Автор), Xuehong Zhang (Автор)
• Формат: Книга
• Опубліковано: BMC, 2024-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background Oxidative stress (OS) is one of the major causes of ovarian aging and dysfunction. Indole-3-propionic acid (IPA) is an indole compound derived from tryptophan with free radical scavenging and antioxidant properties, and thus may have potential applications in protecting ovarian f...