Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free system
Abstract Background Alzheimer's disease is a neurodegenerative disease characterized by the interstitial deposition of amyloid β (Aβ) plaque, which is thought to be related to chronic neuroinflammation. Aβ is known to make fibrils via oligomers from monomers. Aβ has been reported to activate th...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2018-11-01T00:00:00Z.
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| Subjects: | |
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