Intranasal nanocrystals of tadalafil: in vitro characterisation and in vivo pharmacokinetic study
Tadalafil (TDA) is a class II drug of the biopharmaceuticals classification system (BCS), with limited aqueous solubility and high permeability. This study aims to improve the bioavailability of poorly soluble tadalafil by developing intranasal nanocrystals (NCs) of TDA. TDA NCs that were stabilised...
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Format: | Book |
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Pensoft Publishers,
2024-10-01T00:00:00Z.
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