Show a Threshold Effect in Response to Radiation

We investigate the biological effects of radiation using adult Drosophila melanogaster as a model organism, focusing on gene expression and lifespan analysis to determine the effect of different radiation doses. Our results support a threshold effect in response to radiation: no effect on lifespan a...

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Bibliographic Details
Main Authors: Michael Antosh (Author), David Fox (Author), Thomas Hasselbacher (Author), Robert Lanou (Author), Nicola Neretti (Author), Leon N. Cooper (Author)
Format: Book
Published: SAGE Publishing, 2014-10-01T00:00:00Z.
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Summary:We investigate the biological effects of radiation using adult Drosophila melanogaster as a model organism, focusing on gene expression and lifespan analysis to determine the effect of different radiation doses. Our results support a threshold effect in response to radiation: no effect on lifespan and no permanent effect on gene expression is seen at incident radiation levels below 100 J/kg. We also find that it is more appropriate to compare radiation effects in flies using the absorbed energy rather than incident radiation levels.
Item Description:1559-3258
10.2203/dose-response.13-047.Antosh