Show a Threshold Effect in Response to Radiation
We investigate the biological effects of radiation using adult Drosophila melanogaster as a model organism, focusing on gene expression and lifespan analysis to determine the effect of different radiation doses. Our results support a threshold effect in response to radiation: no effect on lifespan a...
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| Main Authors: | , , , , , |
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| Format: | Book |
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SAGE Publishing,
2014-10-01T00:00:00Z.
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| 001 | doaj_178f76b67a0541b4a8c97305731e2d0f | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Michael Antosh |e author |
| 700 | 1 | 0 | |a David Fox |e author |
| 700 | 1 | 0 | |a Thomas Hasselbacher |e author |
| 700 | 1 | 0 | |a Robert Lanou |e author |
| 700 | 1 | 0 | |a Nicola Neretti |e author |
| 700 | 1 | 0 | |a Leon N. Cooper |e author |
| 245 | 0 | 0 | |a Show a Threshold Effect in Response to Radiation |
| 260 | |b SAGE Publishing, |c 2014-10-01T00:00:00Z. | ||
| 500 | |a 1559-3258 | ||
| 500 | |a 10.2203/dose-response.13-047.Antosh | ||
| 520 | |a We investigate the biological effects of radiation using adult Drosophila melanogaster as a model organism, focusing on gene expression and lifespan analysis to determine the effect of different radiation doses. Our results support a threshold effect in response to radiation: no effect on lifespan and no permanent effect on gene expression is seen at incident radiation levels below 100 J/kg. We also find that it is more appropriate to compare radiation effects in flies using the absorbed energy rather than incident radiation levels. | ||
| 546 | |a EN | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Dose-Response, Vol 12 (2014) | |
| 787 | 0 | |n https://doi.org/10.2203/dose-response.13-047.Antosh | |
| 787 | 0 | |n https://doaj.org/toc/1559-3258 | |
| 856 | 4 | 1 | |u https://doaj.org/article/178f76b67a0541b4a8c97305731e2d0f |z Connect to this object online. |