A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by annular patches with slightly raised borders, hypopigmented and/or atrophic centers found mainly on sun-exposed skin. Histologically, it is characterized by phagocytosis of elastic fibers by multin...

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Bibliographic Details
Main Authors: Xiaoping Liu (Author), Wei Zhang (Author), Yeqiang Liu (Author), Mingyuan Xu (Author)
Format: Book
Published: Karger Publishers, 2018-06-01T00:00:00Z.
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Summary:Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by annular patches with slightly raised borders, hypopigmented and/or atrophic centers found mainly on sun-exposed skin. Histologically, it is characterized by phagocytosis of elastic fibers by multinucleated giant cells. The pathogenesis of the disease is unclear. We report a case of 55-year-old man with AEGCG in association with syphilis, whose condition improved when hydroxychloroquine sulfate and topical tacrolimus were administered over a 2-month period.
Item Description:1662-6567
10.1159/000489910