Clinical, genetic, and pathological features of male pseudohermaphroditism in dog

<p>Abstract</p> <p>Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjace...

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Main Authors: Passeri Benedetta (Author), Wohlsein Peter (Author), De Lorenzi Lisa (Author), Peressotti Paolo (Author), Parma Pietro (Author), Bigliardi Enrico (Author), Jottini Stefano (Author), Cantoni Anna (Author)
Format: Book
Published: BMC, 2011-01-01T00:00:00Z.
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Summary:<p>Abstract</p> <p>Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.</p>
Item Description:10.1186/1477-7827-9-12
1477-7827