Enhancement of Atorvastatin Tablet Dissolution Using Acid Medium
In this study some generic commercial products of Atorvastatin tablets were evaluated by dissolution test in acid medium by comparing with that of parent drug Lipitor of Pfizer Company. Some of solubilizing agents were studied in formulation of Atorvastatin tablet including; surface active agent ...
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College of Pharmacy University of Baghdad,
2017-02-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_183721b24c83431d93a7fc92825a067f | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Kahtan j.Hasson |e author |
| 245 | 0 | 0 | |a Enhancement of Atorvastatin Tablet Dissolution Using Acid Medium |
| 260 | |b College of Pharmacy University of Baghdad, |c 2017-02-01T00:00:00Z. | ||
| 500 | |a 2521-3512 | ||
| 500 | |a 1683-3597 | ||
| 520 | |a In this study some generic commercial products of Atorvastatin tablets were evaluated by dissolution test in acid medium by comparing with that of parent drug Lipitor of Pfizer Company. Some of solubilizing agents were studied in formulation of Atorvastatin tablet including; surface active agent and PEG 6000 .The most effective factor was the use of PEG6000 in formulation of Atorvastatin tablet which improved the dissolution and the results of dissolution profile of formulated tablet in this work was bioequivalent to that of Lipitor .The quantitative analysis of this work was performed by using reversed phase liquid chromatography and a proper mixture of mobile phase which give a retention time for Atorvastatin about 6 minutes . | ||
| 546 | |a EN | ||
| 690 | |a Enhancement of Atorvastatin Tablet Dissolution Using Acid Medium | ||
| 690 | |a Pharmacy and materia medica | ||
| 690 | |a RS1-441 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Iraqi Journal of Pharmaceutical Sciences, Vol 19, Iss 1 (2017) | |
| 787 | 0 | |n https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/195 | |
| 787 | 0 | |n https://doaj.org/toc/2521-3512 | |
| 787 | 0 | |n https://doaj.org/toc/1683-3597 | |
| 856 | 4 | 1 | |u https://doaj.org/article/183721b24c83431d93a7fc92825a067f |z Connect to this object online. |