Omalizumab Use in Chronic Spontaneous Urticaria during Pregnancy and a Four Years' Follow-Up: A Case Report

Chronic spontaneous urticaria (CSU) is a benign skin disorder usually responsive to treatment; however, at times it can be difficult to control and become very debilitating. We discuss the case of a woman with CSU that was unresponsive to H1-antihistamines who was treated with omalizumab and became...

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Main Authors: Laura Michelina Losappio (Author), Corrado Mirone (Author), Jan Walter Schroeder (Author), Joseph Scibilia (Author), Luca Balossi (Author), Elide Anna Pastorello (Author)
Format: Book
Published: Karger Publishers, 2020-10-01T00:00:00Z.
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100 1 0 |a Laura Michelina Losappio  |e author 
700 1 0 |a Corrado Mirone  |e author 
700 1 0 |a Jan Walter Schroeder  |e author 
700 1 0 |a Joseph Scibilia  |e author 
700 1 0 |a Luca Balossi  |e author 
700 1 0 |a Elide Anna Pastorello  |e author 
245 0 0 |a Omalizumab Use in Chronic Spontaneous Urticaria during Pregnancy and a Four Years' Follow-Up: A Case Report 
260 |b Karger Publishers,   |c 2020-10-01T00:00:00Z. 
500 |a 1662-6567 
500 |a 10.1159/000509179 
520 |a Chronic spontaneous urticaria (CSU) is a benign skin disorder usually responsive to treatment; however, at times it can be difficult to control and become very debilitating. We discuss the case of a woman with CSU that was unresponsive to H1-antihistamines who was treated with omalizumab and became pregnant during omalizumab treatment. We also considered the follow-up of the mother and newborn for 4 years after delivery. Our case report confirms that omalizumab is a safe and effective therapeutic option, after careful evaluations in terms of cost-effectiveness, in pregnant and lactating women with severe chronic urticaria. Assessment throughout follow-up confirmed a regular progression of pregnancy parameters and no adverse reaction was documented in the child from birth to 4 years of age. 
546 |a EN 
690 |a urticaria 
690 |a pregnancy 
690 |a omalizumab 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Case Reports in Dermatology, Vol 12, Iss 3, Pp 174-177 (2020) 
787 0 |n https://www.karger.com/Article/FullText/509179 
787 0 |n https://doaj.org/toc/1662-6567 
856 4 1 |u https://doaj.org/article/183f5d93e8a646dbbcb3e21f1e7076a9  |z Connect to this object online.