SYNTHESIS OF OLIGOPEPTIDES OF DEFINED FRAGMENT COMPOSITION
The advantages of the solid-phase peptide synthesis were used. The peptide chain was built on specially processed insoluble polymer resin: Wang- and Rink Amide MBHA-resin. Three new fragment oligopeptides were prepared by activation and condensation of Fmoc-protected amino acids [which were subject...
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Main Authors: | , , |
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Format: | Book |
Published: |
Peytchinski Publishing,
2011-05-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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Summary: | The advantages of the solid-phase peptide synthesis were used. The peptide chain was built on specially processed insoluble polymer resin: Wang- and Rink Amide MBHA-resin. Three new fragment oligopeptides were prepared by activation and condensation of Fmoc-protected amino acids [which were subject of our previous work]. One of the important advantages of Fmoc-strategy is achieved: no continuous unblocking of the protection group is effected and the formed peptide bonds do not break. |
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Item Description: | 1312-773X |