SYNTHESIS OF OLIGOPEPTIDES OF DEFINED FRAGMENT COMPOSITION

The advantages of the solid-phase peptide synthesis were used. The peptide chain was built on specially processed insoluble polymer resin: Wang- and Rink Amide MBHA-resin. Three new fragment oligopeptides were prepared by activation and condensation of Fmoc-protected amino acids [which were subject...

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Bibliographic Details
Main Authors: Tamara Paypanova (Author), Tatyana Hristova (Author), Rumyana Cherkezova (Author)
Format: Book
Published: Peytchinski Publishing, 2011-05-01T00:00:00Z.
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Summary:The advantages of the solid-phase peptide synthesis were used. The peptide chain was built on specially processed insoluble polymer resin: Wang- and Rink Amide MBHA-resin. Three new fragment oligopeptides were prepared by activation and condensation of Fmoc-protected amino acids [which were subject of our previous work]. One of the important advantages of Fmoc-strategy is achieved: no continuous unblocking of the protection group is effected and the formed peptide bonds do not break.
Item Description:1312-773X