Ticlopidine-induced subacute cutaneous lupus erythematosus: A case report and literature review

Many drugs have been reported to induce lupus in a minority of patients. Ticlopidine hydrochloride inhibits platelet aggregation and is widely used for the prevention of thrombosis. There have been only a few reports of ticlopidine-induced lupus. Here, we review 13 previously reported cases and desc...

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Main Authors: Yi-Ching Chen (Author), Yu-Hung Wu (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2014-09-01T00:00:00Z.
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100 1 0 |a Yi-Ching Chen  |e author 
700 1 0 |a Yu-Hung Wu  |e author 
245 0 0 |a Ticlopidine-induced subacute cutaneous lupus erythematosus: A case report and literature review 
260 |b Wolters Kluwer Medknow Publications,   |c 2014-09-01T00:00:00Z. 
500 |a 1027-8117 
500 |a 10.1016/j.dsi.2014.01.001 
520 |a Many drugs have been reported to induce lupus in a minority of patients. Ticlopidine hydrochloride inhibits platelet aggregation and is widely used for the prevention of thrombosis. There have been only a few reports of ticlopidine-induced lupus. Here, we review 13 previously reported cases and describe the case of a 71-year-old man with ticlopidine-induced subacute cutaneous lupus erythematosus. His diagnosis was supported by the appearance of papulosquamous skin lesions on sun-exposed areas and detectable anti-Ro/SS-A antibodies, shortly after drug initiation as well as the gradual resolution of these symptoms after the discontinuation of ticlopidine. Our case highlights that when a patient presents with subacute cutaneous lupus erythematosus-like skin lesions, ticlopidine should be considered as a potential causative agent. 
546 |a EN 
690 |a lupus erythematosus 
690 |a ticlopidine 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Dermatologica Sinica, Vol 32, Iss 3, Pp 183-186 (2014) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S1027811714000020 
787 0 |n https://doaj.org/toc/1027-8117 
856 4 1 |u https://doaj.org/article/189b80c7b0dd42688c57aadc7bbba9b1  |z Connect to this object online.