Synthesis, antibacterial and anticancer activity, and docking study of aminoguanidines containing an alkynyl moiety

• Main Authors: Xianqing Deng (Author), Mingxia Song (Author)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Two series of aminoguanidines containing an alkynyl moiety were designed, synthesised, and screened for antibacterial and anticancer activities. Generally, the series 3a-3j with a 1,2-diphenylethyne exhibited better antibacterial activity than the other series (6a-6k) holding 1,4-diphenylbuta-1,3-di...