Systematic investigation of the underlying mechanisms of GLP-1 receptor agonists to prevent myocardial infarction in patients with type 2 diabetes mellitus using network pharmacology

• প্রধান লেখক: Guorong Deng (লেখক), Jiajia Ren (লেখক), Ruohan Li (লেখক), Minjie Li (লেখক), Xuting Jin (লেখক), Jiamei Li (লেখক), Jueheng Liu (লেখক), Ya Gao (লেখক), Jingjing Zhang (লেখক), Xiaochuang Wang (লেখক), Gang Wang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Several clinical trials have demonstrated that glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) reduce the incidence of non-fatal myocardial infarction (MI) in patients with type 2 diabetes mellitus (T2DM). However, the underlying mechanism remains unclear. In this study, we...