The enigma of an EBV - Positive mucocutaneous ulcer: A case report and brief review of literature

Epstein-Barr virus mucocutaneous ulcer (EBVMCU) was first described by Dojcinov et al. in 2010 as a lymphoproliferative disorder presenting with a circumscribed cutaneous or mucosal ulcer in the setting of immunosuppression or immune senescence. Histologically, EBVMCUs show a polymorphous infiltrate...

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Bibliographic Details
Main Authors: Nikita J. Mulchandani (Author), Ann Kurian (Author), K. Kalaichelvi (Author), Kannan Subbiah (Author), Annapurneswari Subramanyan (Author)
Format: Book
Published: Elsevier, 2022-03-01T00:00:00Z.
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Summary:Epstein-Barr virus mucocutaneous ulcer (EBVMCU) was first described by Dojcinov et al. in 2010 as a lymphoproliferative disorder presenting with a circumscribed cutaneous or mucosal ulcer in the setting of immunosuppression or immune senescence. Histologically, EBVMCUs show a polymorphous infiltrate of large B-cells with Hodgkin/Reed-Sternberg (HRS) - like cells intermixed with plasmacytoid cells and T cells which may be reminiscent of lymphomas. However, these lesions usually show an indolent disease course followed by spontaneous remission. In this article we present the case of a 33 year old immunocompetent male diagnosed with EBVMCU and also a review of oropharyngeal EBVMCUs.
Item Description:2772-736X
10.1016/j.hpr.2022.300591