Ultrasmall Solid-Lipid Nanoparticles via the Polysorbate Sorbitan Phase-Inversion Temperature Technique: A Promising Vehicle for Antioxidant Delivery into the Skin

• Main Authors: Francesca Della Sala (Author), Assunta Borzacchiello (Author), Chiara Dianzani (Author), Elisabetta Muntoni (Author), Monica Argenziano (Author), Maria Teresa Capucchio (Author), Maria Carmen Valsania (Author), Annalisa Bozza (Author), Sara Garelli (Author), Maria Di Muro (Author), Franco Scorziello (Author), Luigi Battaglia (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin's lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum corneum. The efficacy of both phenomena cor...