ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT
Objective: To explore the profile of adverse events associated with interferon therapy. Design: Systematic review. Data sources: Electronic and paper records in subject area from 2000 to 2014. Methods: We searched for the studies on safety and tolerability containing adverse events of interferons wi...
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| Format: | Book |
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Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»,
2018-02-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_19705534fb8b4f59b37b56f9c3b3a18f | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a A. A. Toporov |e author |
| 700 | 1 | 0 | |a A. S. Kolbin |e author |
| 245 | 0 | 0 | |a ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT |
| 260 | |b Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products», |c 2018-02-01T00:00:00Z. | ||
| 500 | |a 2312-7821 | ||
| 500 | |a 2619-1164 | ||
| 520 | |a Objective: To explore the profile of adverse events associated with interferon therapy. Design: Systematic review. Data sources: Electronic and paper records in subject area from 2000 to 2014. Methods: We searched for the studies on safety and tolerability containing adverse events of interferons with systemic effect. Results: The most frequent adverse events were: flu-like syndrome (55%), depression (30%), neutropenia (20%), anemia (13%). Conclusion: Adverse events are a very serious problem of interferon treatment. System of pharmacovigilance provides forecasting and early identification of these adverse events, as they are predictable. | ||
| 546 | |a RU | ||
| 690 | |a нежелательные явления | ||
| 690 | |a интерфероны | ||
| 690 | |a фармаконадзор | ||
| 690 | |a adverse event | ||
| 690 | |a pharmacovigilance | ||
| 690 | |a interferon | ||
| 690 | |a side effect | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Безопасность и риск фармакотерапии, Vol 0, Iss 2, Pp 5-11 (2018) | |
| 787 | 0 | |n https://www.risksafety.ru/jour/article/view/10 | |
| 787 | 0 | |n https://doaj.org/toc/2312-7821 | |
| 787 | 0 | |n https://doaj.org/toc/2619-1164 | |
| 856 | 4 | 1 | |u https://doaj.org/article/19705534fb8b4f59b37b56f9c3b3a18f |z Connect to this object online. |