Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation

• Main Authors: M. van der Vaart (Author), O. Svoboda (Author), B. G. Weijts (Author), R. Espín-Palazón (Author), V. Sapp (Author), T. Pietri (Author), M. Bagnat (Author), A. R. Muotri (Author), D. Traver (Author)
• Format: Book
• Published: The Company of Biologists, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mutations in MECP2 cause Rett syndrome, a severe neurological disorder with autism-like features. Duplication of MECP2 also causes severe neuropathology. Both diseases display immunological abnormalities that suggest a role for MECP2 in controlling immune and inflammatory responses. Here, we used me...