Arctigenin Suppressed Epithelial-Mesenchymal Transition Through Wnt3a/β-Catenin Pathway in PQ-Induced Pulmonary Fibrosis

• Main Authors: Fei Gao (Author), Yun Zhang (Author), Zhizhou Yang (Author), Mengmeng Wang (Author), Zhiyi Zhou (Author), Wei Zhang (Author), Yi Ren (Author), Xiaoqin Han (Author), Mei Wei (Author), Zhaorui Sun (Author), Shinan Nie (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Arctigenin (ATG), a major bioactive substance of Fructus Arctii, counters renal fibrosis; however, whether it protects against paraquat (PQ)-induced lung fibrosis remains unknown. The present study was to determine the effect of ATG on PQ-induced lung fibrosis in a mouse model and the underlying mec...