Anticonvulsant Effects of Fuzi Total Alkaloid on Pentylenetetrazole-Induced Seizure in Mice

• मुख्य लेखकों: Bingjin Li (लेखक), Fang Tang (लेखक), Liang Wang (लेखक), Lei Liu (लेखक), Jing Zhao (लेखक), Yang Zhou (लेखक), Yinuo Wang (लेखक), Yunong Song (लेखक), Yuxin Li (लेखक), Ranji Cui (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2013-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We investigated the anticonvulsant effect of acute Fuzi total alkaloid (FTA) in seizure induced by the GABAA-receptor antagonist pentylenetetrazole (PTZ). FTA significantly increased the seizure latency and decreased the mortality in PTZ-treated mice. Administration of PTZ increased c-Fos expression...