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Anticonvulsant Effects of Fuzi Total Alkaloid on Pentylenetetrazole-Induced Seizure in Mice

We investigated the anticonvulsant effect of acute Fuzi total alkaloid (FTA) in seizure induced by the GABAA-receptor antagonist pentylenetetrazole (PTZ). FTA significantly increased the seizure latency and decreased the mortality in PTZ-treated mice. Administration of PTZ increased c-Fos expression...

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Main Authors: Bingjin Li (Author), Fang Tang (Author), Liang Wang (Author), Lei Liu (Author), Jing Zhao (Author), Yang Zhou (Author), Yinuo Wang (Author), Yunong Song (Author), Yuxin Li (Author), Ranji Cui (Author)
Format: Book
Published: Elsevier, 2013-01-01T00:00:00Z.
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