Development of a UV-Stabilized Topical Formulation of Nifedipine for the Treatment of Raynaud Phenomenon and Chilblains

• Main Authors: Ellen K. Wasan (Author), Jinying Zhao (Author), Joshua Poteet (Author), Munawar A. Mohammed (Author), Jaweria Syeda (Author), Kevin Soulsbury (Author), Jacqueline Cawthray (Author), Amanda Bunyamin (Author), Chi Zhang (Author), Brian M. Fahlman (Author), Ed S. Krol (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Raynaud’s Phenomenon is a vascular affliction resulting in pain and blanching of the skin caused by excessive and prolonged constriction of arterioles, usually due to cold exposure. Nifedipine is a vasodilatory calcium channel antagonist, which is used orally as the first-line pharmacologi...