Effects of <it>Sophora japonica </it>flowers (<it>Huaihua</it>) on cerebral infarction

<p>Abstract</p> <p>The dried flowers and buds of <it>Sophora japonica </it>are used as a medicinal herb in China, Japan and Korea to treat bleeding hemorrhoids and hematemesis. This article presents an overview of the effects of <it>Sophora japonica </it>on...

Full description

Saved in:
Bibliographic Details
Main Authors: Hsieh Ching-Liang (Author), Chen Hsiang-Ni (Author)
Format: Book
Published: BMC, 2010-09-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:<p>Abstract</p> <p>The dried flowers and buds of <it>Sophora japonica </it>are used as a medicinal herb in China, Japan and Korea to treat bleeding hemorrhoids and hematemesis. This article presents an overview of the effects of <it>Sophora japonica </it>on cerebral infarction based on literature searched from Medline, PubMed, Cochrane Library and the China National Knowledge Infrastructure (CNKI). <it>Sophora japonica </it>contains both anti-hemorrhagic and anti-hemostatic substances. <it>Sophora japonica </it>reduces cerebral infarction partly as a result of its anti-oxidative and anti-inflammatory activities. Previous studies found that <it>Sophora japonica </it>reduced the size of cerebral infarction and neurological deficits and reduced microglial activation, interleukin-1β release and number of apoptotic cells in ischemia-reperfusion injured Sprague-Dawley rats. Further study is required to determine the relationship between <it>Sophora japonica</it>-mediated reduction in cerebral infarction size and the effects of <it>Sophora japonica </it>on platelet aggregation and cardiovascular function.</p>
Item Description:10.1186/1749-8546-5-34
1749-8546