Calcineurin A (Ca) Inhibition Supresses Protein Synthesis Via Amp Dependent Kinase (Ampk).
Diabetes stimulates CA activity in the kidney and CA inhibitor cyclosporine A (CYA) or CAβ isoform knock-out (CAβ -/-) block diabetic renal hypertrophy.CA regulates the mammalian target of rapamycin (mTOR) to reduce protein synthesis (PS) during cardiac hypertrophy.To study this pathway, NRK-52E and...
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Main Authors: | H. Franch (Author), C. Ding (Author), S. Zoromsky (Author), S. Williams (Author), J. Gooch (Author) |
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Format: | Book |
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The Korean Society of Nephrology,
2012-06-01T00:00:00Z.
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