Small Molecule Inhibitors of CRM1
The transport through the nuclear pore complex is used by cancer cells to evade tumor-suppressive mechanisms. Several tumor-suppressors have been shown to be excluded from the cell nucleus in cancer cells by the nuclear export receptor CRM1 and abnormal expression of CRM1 is oncogenic. Inhibition of...
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Frontiers Media S.A.,
2020-05-01T00:00:00Z.
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