Seeing the random forest through the decision trees. Supporting learning health systems from histopathology with machine learning models: Challenges and opportunities

This paper discusses some overlooked challenges faced when working with machine learning models for histopathology and presents a novel opportunity to support "Learning Health Systems" with them. Initially, the authors elaborate on these challenges after separating them according to their...

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Bibliographic Details
Main Authors: Ricardo Gonzalez (Author), Ashirbani Saha (Author), Clinton J.V. Campbell (Author), Peyman Nejat (Author), Cynthia Lokker (Author), Andrew P. Norgan (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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Summary:This paper discusses some overlooked challenges faced when working with machine learning models for histopathology and presents a novel opportunity to support "Learning Health Systems" with them. Initially, the authors elaborate on these challenges after separating them according to their mitigation strategies: those that need innovative approaches, time, or future technological capabilities and those that require a conceptual reappraisal from a critical perspective. Then, a novel opportunity to support ''Learning Health Systems'' by integrating hidden information extracted by ML models from digitalized histopathology slides with other healthcare big data is presented.
Item Description:2153-3539
10.1016/j.jpi.2023.100347