Differential Effects of the Mitochondria-Active Tetrapeptide SS-31 (D-Arg-dimethylTyr-Lys-Phe-NH2) and Its Peptidase-Targeted Prodrugs in Experimental Acute Kidney Injury
The mitochondria-active tetrapeptide SS-31 can control oxidative tissue damage in kidney diseases. To investigate other potential beneficial nephroprotective effects of SS-31, in vivo murine models of acute tubular injury and glomerular damage were developed. Reduction of acute kidney injury was dem...
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Main Authors: | Jean-Christophe Wyss (Author), Rajesh Kumar (Author), Josip Mikulic (Author), Manfred Schneider (Author), Jean-Luc Mary (Author), Johannes D. Aebi (Author), Lucienne Juillerat-Jeanneret (Author), Dela Golshayan (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2019-11-01T00:00:00Z.
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