Model-Informed Precision Dosing of Antibiotics in Pediatric Patients: A Narrative Review

• Main Authors: Alan Abdulla (Author), Elma Edwina (Author), Robert B. Flint (Author), Karel Allegaert (Author), Enno D. Wildschut (Author), Birgit C. P. Koch (Author), Matthijs de Hoog (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Optimal pharmacotherapy in pediatric patients with suspected infections requires understanding and integration of relevant data on the antibiotic, bacterial pathogen, and patient characteristics. Because of age-related physiological maturation and non-maturational covariates (e.g., disease state, in...