CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis

• Main Authors: James Crooks (Author), Marco Gargaro (Author), Carmine Vacca (Author), Claudia Volpi (Author), Matteo Pirro (Author), Giulia Scalisi (Author), Antonella Turco (Author), Rita Romani (Author), Davide Matino (Author), Abdolmohamad Rostami (Author), Paolo Puccetti (Author), Bruno Gran (Author), Francesca Fallarino (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2017-01-01T00:00:00Z.
• Fag: article
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Experimental autoimmune encephalomyelitis (EAE) is an inflammatory, demyelinating disease of the CNS that mimics human multiple sclerosis (MS), and it is thought to be driven by Th1 and Th17 myelin-reactive cells. Although adaptive immunity is clearly pivotal in the pathogenesis of EAE, with an esse...