CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis

• Главные авторы: James Crooks (Автор), Marco Gargaro (Автор), Carmine Vacca (Автор), Claudia Volpi (Автор), Matteo Pirro (Автор), Giulia Scalisi (Автор), Antonella Turco (Автор), Rita Romani (Автор), Davide Matino (Автор), Abdolmohamad Rostami (Автор), Paolo Puccetti (Автор), Bruno Gran (Автор), Francesca Fallarino (Автор)
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• Опубликовано: Hindawi Limited, 2017-01-01T00:00:00Z.
• Предметы: article
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Experimental autoimmune encephalomyelitis (EAE) is an inflammatory, demyelinating disease of the CNS that mimics human multiple sclerosis (MS), and it is thought to be driven by Th1 and Th17 myelin-reactive cells. Although adaptive immunity is clearly pivotal in the pathogenesis of EAE, with an esse...