Antisense oligonucleotides: a novel Frontier in pharmacological strategy

• Main Authors: D. Collotta (Author), I. Bertocchi (Author), E. Chiapello (Author), M. Collino (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Antisense oligonucleotides (ASOs) are short single stranded synthetic RNA or DNA molecules, whereas double-stranded RNA nucleotide sequences are called small interfering RNA (siRNA). ASOs bind to complementary nucleic acid sequences impacting the associated functions of the targeted nucleic acids. T...