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Pharmacokinetic comparative study of tropoxine metabolite in miscellaneous animal species and humans

Results of pharmacokinetic study of tropoxine metabolite (tropinone oxime; M-1) in experimental animals (rats, rabbits) and humans after administration several doses of tropoxine. Comparative analysis of the pharmacokinetic parameters characterizing of the metabolite formation intensity, i.e. Cmax o...

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Main Authors: V. P. Zherdev (Author), G. B. Kolyvanov (Author), A. A. Litvin (Author), P. O. Bochkov (Author), R. V. Shevchenko (Author), O. G. Grybakina (Author), T. S. Ganshina (Author)
Format: Book
Published: LLC "Publisher OKI", 2017-03-01T00:00:00Z.
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Summary:Results of pharmacokinetic study of tropoxine metabolite (tropinone oxime; M-1) in experimental animals (rats, rabbits) and humans after administration several doses of tropoxine. Comparative analysis of the pharmacokinetic parameters characterizing of the metabolite formation intensity, i.e. Cmax of metabolite M-1 in the blood plasma increased in series: rats>humans> rabbits. Elimination rate of M-1 was decreased in series: rats>rabbits>humans
Item Description:2587-7836
2686-8830

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