Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis

• Main Authors: Francisco Javier Ruiz-Ojeda (Author), Jiefu Wang (Author), Theresa Bäcker (Author), Martin Krueger (Author), Samira Zamani (Author), Simon Rosowski (Author), Tim Gruber (Author), Yasuhiro Onogi (Author), Annette Feuchtinger (Author), Tim J. Schulz (Author), Reinhard Fässler (Author), Timo D. Müller (Author), Cristina García-Cáceres (Author), Matthias Meier (Author), Matthias Blüher (Author), Siegfried Ussar (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Reorganization of the extracellular matrix is a prerequisite for healthy adipose tissue expansion, whereas fibrosis is a key feature of adipose dysfunction and inflammation. However, very little is known about the direct effects of impaired cell-matrix interaction in adipocyte function an...