Pharmacokinetics and metabolism of cyadox and its main metabolites in beagle dogs following oral, intramuscular and intravenous administration

• Main Authors: Adeel Sattar (Author), Shuyu Xie (Author), Lingli Huang (Author), Zahid Iqbal (Author), Wei Qu (Author), Muhammad Abubakr Shabbir (Author), Yuanhu Pan (Author), Hafiz Iftikhar Hussain (Author), Dongmei Chen (Author), Yanfei Tao (Author), Zhenli Liu (Author), Mujahid Iqbal (Author), Zonghui Yuan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cyadox (Cyx) is an antibacterial drug of the quinoxaline group that exerts markedly lower toxicity in animals, compared to its congeners. Here, the pharmacokinetics and metabolism of Cyx after oral (PO), intramuscular (IM) and intravenous (IV) routes of administration were studied to establish safet...