Restoration of motor learning in a mouse model of Rett syndrome following long-term treatment with a novel small-molecule activator of TrkB
Reduced expression of brain-derived neurotrophic factor (BDNF) and impaired activation of the BDNF receptor, tropomyosin receptor kinase B (TrkB; also known as Ntrk2), are thought to contribute significantly to the pathophysiology of Rett syndrome (RTT), a severe neurodevelopmental disorder caused b...
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Main Authors: | Ian Adams (Author), Tao Yang (Author), Frank M. Longo (Author), David M. Katz (Author) |
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Format: | Book |
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The Company of Biologists,
2020-11-01T00:00:00Z.
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