NRF2 Activation Ameliorates Oxidative Stress and Improves Mitochondrial Function and Synaptic Plasticity, and in A53T α-Synuclein Hippocampal Neurons
In Parkinson's disease (PD), brain oxidative stress and mitochondrial dysfunction contribute to neuronal loss as well as motor and cognitive deficits. The transcription factor NRF2 has emerged as a promising therapeutic target in PD because it sits at the intersection of antioxidant and mitocho...
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Main Authors: | Mikah S. Brandes (Author), Jonathan A. Zweig (Author), Anita Tang (Author), Nora E. Gray (Author) |
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Format: | Book |
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MDPI AG,
2021-12-01T00:00:00Z.
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