The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease

Artemisinin (ARS) and its derivatives (ARSs) are recommended as the first-line antimalarial drugs for the treatment of malaria. Besides antimalarial function, its potent anti-inflammatory and immunoregulatory properties, as well as the ability to regulate oxidative stress have brought them to a prom...

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Bibliographic Details
Main Authors: Ming Xia (Author), Di Liu (Author), Yu Liu (Author), Hong Liu (Author)
Format: Book
Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
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100 1 0 |a Ming Xia  |e author 
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700 1 0 |a Yu Liu  |e author 
700 1 0 |a Hong Liu  |e author 
245 0 0 |a The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease 
260 |b Frontiers Media S.A.,   |c 2020-03-01T00:00:00Z. 
500 |a 1663-9812 
500 |a 10.3389/fphar.2020.00380 
520 |a Artemisinin (ARS) and its derivatives (ARSs) are recommended as the first-line antimalarial drugs for the treatment of malaria. Besides antimalarial function, its potent anti-inflammatory and immunoregulatory properties, as well as the ability to regulate oxidative stress have brought them to a prominent position. As researchers around the world are continually exploring the unknown biological activities of ARS derivatives, experimental studies have shown much progress in renal therapy. This review aims to give a brief overview of the current research on ARSs applications for kidney treatment with the evaluation of therapeutic properties and potential molecular mechanisms. 
546 |a EN 
690 |a artemisinin derivatives (artemisinins) 
690 |a kidney disease 
690 |a inflammation 
690 |a immunity 
690 |a oxidative stress 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
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786 0 |n Frontiers in Pharmacology, Vol 11 (2020) 
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