Autoimmune progesterone dermatitis manifesting as generalized fixed drug eruption

Abstract: Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens. Most cases manifest as urticaria, eczema or erythema multiforme-like. A 26-year-old woman developed violaceous plaques...

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Bibliographic Details
Main Authors: Juan Eduardo Carrasco-Zuber (Author), Sergio Álvarez-Véliz (Author), Catherina Moll-Manzur (Author), Sergio González-Bombardiere (Author)
Format: Book
Published: Sociedade Brasileira de Dermatologia, 2018-12-01T00:00:00Z.
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Summary:Abstract: Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens. Most cases manifest as urticaria, eczema or erythema multiforme-like. A 26-year-old woman developed violaceous plaques on the groin and abdomen, 4 days after a spontaneous abortion resolved with uterine curettage. The lesions recurred once monthly at the same sites, mimicking a fixed drug eruption. Although the histopathology was compatible with fixed drug eruption, positive intradermal testing and symptomatic improvement after using oral contraceptive pills gave us a clue to the diagnosis.
Item Description:0365-0596
10.1590/abd1806-4841.20187290