Spray Dried Levodopa-Doped Powder Potentially for Intranasal Delivery

• Main Authors: Xuan Liu (Author), Shen Yan (Author), Mengyuan Li (Author), Shengyu Zhang (Author), Gang Guo (Author), Quanyi Yin (Author), Zhenbo Tong (Author), Xiao Dong Chen (Author), Winston Duo Wu (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work was aimed to develop levodopa (L-dopa) nasal powder to achieve controllable drug release and high nasal deposition efficiency. A series of uniform microparticles, composed of amorphous L-dopa and excipients of hydroxypropyl methyl cellulose (HPMC), polyvinylpyrrolidone (PVP), or hydroxypro...