SwissPKcdw - A clinical data warehouse for the optimization of pediatric dosing regimens

• Main Authors: Roland Goers (Author), Diana Coman Schmid (Author), Vera F. Jäggi (Author), Paolo Paioni (Author), Michal J. Okoniewski (Author), Althea Parker (Author), Beat Bangerter (Author), Sofia Georgakopoulou (Author), Thierry Sengstag (Author), Julia Bielicki (Author), Romy Tilen (Author), Swen Vermeul (Author), Stefanie D. Krämer (Author), Christoph Berger (Author), Bernd Rinn (Author), Henriette E. Meyer zu Schwabedissen (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Clinical trials have been performed mainly in adults and accordingly the necessary information is lacking for pediatric patients, especially regarding dosage recommendation for approved drugs. This gap in information could be filled with results from pharmacokinetic (PK) modeling, based on...