β-Arrestin-Mediated Signaling Improves the Efficacy of Therapeutics

• Asıl Yazarlar: Islam A.A.E.-H. Ibrahim (Yazar), Hitoshi Kurose (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2012-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

β-Arrestins (β-arrestin-1 and β-arrestin-2) were first identified as proteins that have the ability to desensitize G protein-coupled receptors (GPCRs). However, it has recently been found that β-arrestins can activate signaling pathways independent of G protein activation. The diversity of these sig...